Dare to Defy Time

Thalgo has selected two high performance marine active ingredients:

  • Meristotheca dakaraensis for its ability to protect the epidermis’ structure and stimulate the molecules that make up the dermis.
  • Palmaria palmata, rich in vitamins A, B, C and E as well minerals and essential elements that are part of all organic synthesis process.

and developed three Marine Technologies:

  • Collagen Programm – Smoothing
  • Hyaluronic Programm – Filling
  • Silicum Programm – Lift

that are gentle on the skin, while respecting nature.

This new product line from Thalgo DOES NOT contain:

  • Parabens
  • Mineral Oil
  • Propylene Glycol
  • GMO


The abundant protein in the body, it makes skin elastic and gives it it’s “firm” look.

Collagen Cream

Fine lines fade away day after from the moment this smoothing and repairing, ultra hydrating cream is applied.

Apply morning and/or evening, on its own or after the Concentrate.

Price: $64; 50mL

Collagen Concentrate

This serum, which is highly concentrate in Marine Collagen, instantly smoothes emerging wrinkles. Its revolutionary “second skin” texture leaves a unique matte and velvety finish.

Apply before the Cream as a one month course of treatment. Repeat several times a year.

Price: $72; 30mL

A filling molecule that is essential for proper skin density, it provides support for the epidermis through its water holding abilities.

Hyaluronic Filler

Concentrated in Marine Hyaluronic Acid for a high precision filling effect, it is applied at the heart of the most pronounced wrinkles for an instant smoothing effect!

Apply in the morning under the Cream foe an instant smoothing effect or in the evening for optimal regeneration.

Price: $78; 50mL

Hyaluronic Cream

A real rejuvenating force, it erases fine lines and fills in stubborn wrinkles.

Apply morning and/or evening, on its own or after the Hyaluronic Filler.

Price: $58; 15mL

Hyaluronic Mask

A professional formula with the amazing efficacy: it plumps up the entire face and smoothes and fills in marked wrinkles.

Apply generously. Leave on for 20 minutes. Then rinse off. Use ideally once a week.

Price: $46; 50mL

Naturally present in the body, especially the skin, it is needed to produce the support fibres Collagen and Elastin.

Silicium Extracts – Face Contours & Neck

Your lifting and refining secret rich in Caffeine and Marine Silicum to specially re-sculpt the facial contour area and neck. Apply before the Concentrate or the Cream, as often as necessary.

Price: $72; 15mL

SiIlicium Concentrate

Intense re-firming and re-sulpting skincare, this rich highly concentrated serum amplifies the effects of the cream for an incomparably supple and velvety finish on the skin.

Apply before the Cream as a one month course of treatment. Repeat several times a year.

Price: $102; 30mL

Sillicium Cream

Push the boundaries of anti-aging standards and discover Sillicium Cream. It fills in wrinkles, nourishes your skin and restores its firmness, while re-sculpting the contours of the face. Apply morning and/or evening, on its own or after the Concentrate.

Price: $92; 50mL

To learn more about Thalgo products follow this link.

Hair reduction treatment with High Intensity Pulsed Light (HIPL)*

Hair reduction treatment with High Intensity Pulsed Light (HIPL)*
with GEM** technology
Dr. Ezra H. Nuriel – Neutrino
 
Abstract
Active optical systems Ltd encapsulate more than 25 years of experience in the hair removal field. In the year of 2000 the first device based on light energy was introduced to the market. Since then many improvements were devised and installed and today the company manufacturers the Crystal 512 and the Record 618, hair removal machines. The machines are based on Active’s GEM (Geometrical Energy Management) patented technology. The present research is intended to test this technology and its implementation in two major fields: effectiveness of treatments and the potential treatment side effects.
The research was performed on 2992 patients in different ages, genders, skin and hair colors in order to achieve an accurate picture on the entire population. The research was performed over three years, in 73 different locations, and according to our knowledge this research is one of the largest of its kind, made in this field.
The results show the abilities of the HIPLGEM technology in both fields .
 
Introduction
Investigations (Anderson et Al)[4] has clearly demonstrated that a flash of high intensity light penetrates through the epidermis, absorbed and assimilated in the hair bulbous region and acts as an inhibitor to the hair follicle through temporarily temperature rise and agglutination.
The follicle has several parts of interest:
Dermal papilla  – The dermal papilla directs and dictates the embryonic generation of a hair follicle and retains this instructive ability throughout the life of the hair follicle. It consists of a highly active group of cells shown to be capable of inducing follicle development from the epidermis and the production of hair fiber.
The bigger the Dermal Papilla, the more cells it has – the thicker the hair fiber that the hair follicle produces.
Basement Lamina – The Basement Lamina is a thin layer of cells that separates the Dermal Papilla form the hair sheath cells. Providing a barrier between the dermis and the epidermis.
Matrix cells  – The Matrix cells are Epidermal derived cells close to the Dermal Papilla. These cells remain undifferentiated and focus on multiplying and proliferating to produce more cells. Those cells are located in the center of the hair follicle and designated to become part of the hair
fiber. Their name is Cortex (cortical) cells.
Cortex Cells – the Cortex cells are made by the matrix cells, aimed to become a part of the hair
fiber.
As these cells multiply, the constant stream of production pushes the cells upward towards the skin surface. As they move upwards they begin to differentiate into particular cell types. The cortex cells change from a round into a flattened appearance. They are squeezed together into layers (lamella). If the hair follicle contains melanocyte cells the melanin pigment is incorporated into the cortex cells. These cortex cells become keratinized and hardens. As they do so it becomes impossible for the cells to function properly and the cells die. The keratinized cells are then pushed away from the hair bulb region upwards, as the new cells develop underneath. The cortex cells are now part of the dead keratinized fiber. This is the hair we see.
Capillaries – small blood vessels that brings nutrition and oxygen via the blood stream to the hair follicles and takes away the CO2 and the waste produced in the cell’s metabolic cycle.
When we give a pulse of light, the light penetrates the epidermis and absorbed in the cells.
The darker the area the more energy it will absorb. As it can be seen from Fig.1, the darkest area, is the area of the matrix cells (the cells that produce the hair fiber cells), that had melanin inside the cells.
 

               

 
Figure 1: The construction of the hair bulbous
 Another dark area is the Capillaries area – especially the capillaries that have vain blood in them. Vain blood is darker because it has deoxyhemoglobin, which is not attached to oxygen. 
When we give a pulse of light many matrix cells are coagulated and stop functioning .
Matrix cells, which are not coagulated, are triggered to activate their calcium pumps. According
to Friedmann (1993)[19], a high intensity light pulse will cause a vast calcium release from mitochondria into cytoplasm. The hyperactivity of Ca+2 pumps exhausts the ATP (Adenosine Tri-Phosphate – an energy molecule) pool, denies it form the cells, thereby inhibiting cell metabolism resulting in the production of less Cortex Cells and therefor – less hair or more feathery hair and less terminal hair.
Another effect of the HIPLGEM is the clotting of the vain blood in the capillaries. The clotting disturbs the blood supply to the hair follicle meaning less food and oxygen are delivered to the hair follicle, resulting in a smaller ability to produce hair.
These three effects cause hair reduction and removal. The coagulation is the main reason but the other two effects contribute to the hair loss as well.
Active Optical System’s aim is to achieve 80% hair growth reduction -according to the FDA definition.
90 % of hair growth sites are in the region of 3 mm under skin surface, most of them imbedded in the dermis.  With the HIPLGEM technology we focus the energy on the hair grow sites.
In order to have effective hair reduction and removal significant energies must be applied to the skin. Two antagonist factors must be taken in consideration for successful result: each follicle must be damaged, but the surrounding tissue, especially the epidermis must be protected from damage. Using long wavelength (1100 nm), are much more suitable for deep hair reduction because of reduced scattering in the dermis, and greater penetration depth [5]. The use of broadband light spectrum, gives the advantage of “energizing” the hair follicles [7]. This technique is very effective for hair reduction, as it operates on all the types of hair (not white), and supplies the needed energy to diminish it. The melanin can be effectively targeted by the intense light source throughout the visible light spectrum [4].
Hair growth is a cycle with four stages. The best time to target a follicle is when it is at the first hair growth phase – the Anagen phase. In this phase we will find the largest concentration of melanin and blood supply, which means that in this phase we find the biggest color differentiation between the follicle and its surrounding tissues .
Targeting the follicle at this phase provides us with the best conditions to destroy the hair follicle.
If we fail to destroy the follicle at this phase, the follicle will continue the hair growth cycle and eventually return once more to the Anagen stage according to its natural cycle. The duration of each phase changes according to the anatomical location and varies between several weeks to several months.   
When we apply energy to the skin, the principle of Photothermolysis and the thermal relaxation time should be considered [4,5]. The term of thermal relaxation time is used to determine the limitation of the thermal damage when a designated target absorbs the energy of a given wavelength in a specified period of time. With the right combination of wavelength, duration and energy, it is possible to target a hair follicle without causing any injury to the surrounding tissue. Taking in consideration all the factors mentioned above, we found, that if the light source delivers its energy through a large beam (greater area), short duration (concentrated energy), high intensity (better penetration) and low repetition rate (larger time to cool), an increase of penetration and follicle destruction occurs [16, 17, 18].
This enhances the chance of affecting large area of growth centers, and a greater chance of hair follicle destruction. Moreover, in order to protect the epidermal melanin from damage, a water based cooling gel is applied on the skin surface .
In this research we investigated the abilities of the HIPLGEM technology and its implementation in Active’s machines to achieve permanent hair reduction without significant unwanted side effects.
  
Materials and Methods
In order to conduct this research we used two kind of machines: Crystal 512 (commercial-lamp lifetime 100.000 pulses) and Record 618 (industrial-lamp lifetime 200.000 pulses), all other specifications are identical. Both machines practice the HIPLGEM technology .
The machines are approved by governmental CFS and withstand the medical safety standard IEC 60601-1, IEC 601-1-2 and the CSA standard for Canada and the US. The machines use a technology that manages to concentrate the bulk of the energy to a precise geometric plane, positioned on the selected target (hair follicles, pigmentation, vascular lesions, acne, herpes, skin rejuvenation etc .
Both machines have a broadband wavelength from 450nm up to 1100nm. Large spot size 15x50mm, pulse repetition rate is of 3 to 4 Seconds. The maximum energy, which can be delivered, is 22 J/cm2.
Twelve fully automated computerized programs, intended for most skin types and hair colors, designate the fluency of each pulse (J/cm2).
Due to the targeting, no excessive heat “overloads” the adjacent tissue, this makes the treatment efficient and painless.
The research was conducted in Israel, a sunny country whose population has a high diversity of skin colors. The diversity of skin colors allows us to get a representing picture of the world population from which we can implement on the whole world population .
Since Israel is a sunny country many people are tanned. Tanned skin allows us to use less energy since it will absorb energy just like the follicle’s melanin. Due to smaller color differentiation selective photothermolysis is harder to achieve. The meaning is that if the machines perform well in Israel they will perform well and even better in countries with cooler weather. 
The research was conducted on 2992 patients in order to supply the research team with reliable results that can give a good indication on the machine’s performance.
The research was conducted in 73 different clinics for three years in order to check the performance of the machines compared with the FDA definitions of hair removal and hair reduction.
The aim was to check if the machines could reach 80% of permanent hair reduction without
significant side effects.
During the research each patient was treated according to the manufacturer’s guidelines and protocol. All treatments and patients where monitored and treatment specifications and results where collected.
The treatment intervals and energy where adjusted specifically for each patient, considering skin color, treatment area, hair type. The sensitivity of each new patient was checked to determine the optimal computerized program to be used.
In cases, where the site to be treated is covered with dense hair, pre-shaving was done, to prevent energy absorption by the hair on top of the skin and allow clear way to the hair follicle.
Experience and professional judgment were used to determine the ideal treatment parameters for each patient, this was determined by delivering several test pulses at an inconspicuous site, with equivalent pigmentation, starting at low energy fluency and slowly increasing the energy fluency. Undesirable effects, such as pain, itching, redness, transient erythema, edema, whitening and blistering were to be avoided. Only after the program to be used, is defined for each new patient, the actual treatment at the pre determined sites begin.
 
Results
As mentioned before, 2992 patients were treated with the machines. Each patient was treated with a preset computerized program, appropriate for his skin color, type of hair, the treated area, the hair color, the patient sensitivity etc.
The treatments were preformed on a variety of the body locations except the eyes, the nipples and other sensitive location according to the patient sensitivity .
The fluency used was designated according to many factors, but the main factors taken in consideration were the skin color and the hair color.
The patients received a total of 27763 treatments with the average of 9.3 treatment for each patient .
We can clearly see from Fig.2 that 77.17% (2309 patients – see Fig.3) of the treated patients reached at least 80% of permanent hair reduction. These patients received more than 10 treatments per patient.
9.19% (275 – see Fig.3) patients reached at least 70% of permanent hair reduction – see Fig.2.
Only twenty one patients (see Fig.4) developed mild side effects (0.702% – see Fig.5) which is completely negligible, 16 patients had mild erythema, 3 patients had mild swelling with extremely mild edema, 2 patients felt itching, all the symptoms disappeared within 24 – 48 hours post treatment.
All results were evaluated after completing the treatment session. The first two treatments were done two weeks apart from each other. Each time the treatment was evaluated. The treatments continued with intervals according to the patient’s hair growth cycle timing – until the patient
was satisfied according to the promised expectations.

Source: article

Hair removal using light

Investigations (Anderson et Al) has clearly demonstrated that a flash of
high intensity light penetrated through the epidermis, is absorbed and
assimilated in the hair bulbous region, and acts as inhibitor to the hair
follicle through temporarily temperature rise and agglutination.

The follicle has several parts that interest us.
Dermal papilla – The dermal papilla directs and dictates the embryonic
generation of a hair follicle and it also retains this instructive ability
throughout the life of the hair follicle. It consists of a highly active group
of cells shown to be capable of inducing follicle development from the
epidermis and production of hair fiber (Oliver 1966a, Oliver 1966b,
Oliver 1967).
The bigger the Dermal Papilla is, the more cells it has – the thicker the
hair fiber that the hair follicle produces.

Basement Lamina – a thin layer of cells that separates the Dermal Papilla
form the hair sheath cells. Providing a barrier between the dermis and
epidermis.

Matrix cells – Epidermal derived cells close to the Dermal Papilla. These
cells remain undifferentiated and focus on multiplying and proliferating
to produce more cells. Those cells made in the center of the hair follicle
are destined to become part of the hair fiber and are called Cortex
(cortical) cells.

Cortex Cells – Cells that are made by the matrix cells, aimed to become a
part of the hair fiber.

As these cells multiply, the constant stream of production pushes the cells
upward towards the skin surface. As they move up the hair follicle they
begin to differentiate into particular cell types. The cortex cells change
from a round into a flattened appearance. They are squeezed together into
layers (lamella). If the hair follicle contains melanocyte cells then
melanin pigment is incorporated into the cortex cells. These cortex cells
become keratinized and harden. As they do so it becomes impossible for
the cells to function properly and the cells die. The keratinized cells are
then pushed away from the hair bulb region and upwards as new cells
come in behind. The cortex cells are now part of the dead keratinized
fiber. Which is the hair that we see.

Capillaries – small blood vessels that brings food and oxygen to the hair
follicles and takes away the CO2 and waste of the cells metabolic cycle.

When we give a pulse of light, the light penetrates the epidermis and
absorbs in the cells.

The darker the area the more energy it will absorb. As you can see in the
picture, the darkest area is the area of the matrix cells (the cells that
produce the hair fiber cells). That is because of the melanin, which is
inside these cells.

 

 

Another dark area is the Capillaries area – especially the capillaries that
have vain blood in them. Vain blood is darker because it has hemoglobin,
which is not attached to oxygen.

When we give a pulse of light many matrix cells are coagulated and stop
functioning.

Matrix cells that are not coagulated are triggered to activate their calcium
pumps. According to Friedmann (1993), a high intensity light pulse will
cause a vast calcium release from mitochondria into cytoplasm. The
hyperactivity of Ca+2 pumps exhausts the ATP (an energy molecule) pool
of the cell, thereby inhibiting cell metabolism resulting in the production
of less Cortex Cells and therefor – less hair or more feathery hair.

Another effect of the light pulse is the clotting of the vain blood in the
capillaries. The clotting disturbs the blood flow to the hair follicle
meaning less food and oxygen are delivered to the hair follicle, resulting
in a smaller ability to produce hair.

These three effects are the cause of the hair removal. The coagulation is
the main reason but the other two effects contribute to the hair loss as
well.

The Crystal 512 and Record 618delivers enough light energy, in the right wavelength, in
order to cause these effects but avoids from too much energy that might
influence other areas of the skin.

 

 www.active2001.com

Vascular treatment using light

There are several types of capillaries. The light pulse treats surface “spider” like capillaries, which are small purple or red veins that stretches like a web near the surface of the skin and or typically discolored clusters.

The capillaries get their color due to the existence of clotted RBC (red blood cells).

These capillaries are very narrow. Sometimes blood cells are “stuck” in these capillaries because they are very narrow. Other RBC that comes into that capillary gets stuck behind the first one and form a layer of clotted blood which gives the capillary it’s color.

The capillaries are seen when they are near the surface of the skin or when the skin becomes thin due to loss of the collagen layer.

When we treat the capillaries we have two levels of treatment:

1. We break the layer of clotted blood and open the capillary again, resulting in free blood flow throw the capillary and the disappearance of the purple color.

2. We treat the collagen layer, stimulating it to produce more collagen resulting in wider skin and concealed veins.

The Crystal 512 and Record 618 broad-spectrum wavelengths are absorbed in the hemoglobin of the clotted blood. Clotted RBC are dead RBC. The energy shakes the structure of the RBC layer. It gives the molecules of the layer enough energy to start moving and breaks the connections between them.

When there are single molecules they can pass throw the vein and dissolve in the body. After several treatments the entire layer moves away from the vein and the purple color is gone.

The other part of the treatment is to stimulate the collagen layer to produce more collagen. Resulting in skin rejuvenation and concealing the vein in the new thicker skin.

www.active2001.com

Skin rejuvenation using light

According to findings by Friedmann and co-workers (1993), low doses of light intensify the formation of a transmembrane electrochemical proton gradient in mitochondria.

The process happens upon absorption of mitochondrial chromophores such as cytochromes, which are followed by calcium release from mitochondria into cytoplasm by a calcium/hydrogen antiport system and subsequently triggers mitosis and cell proliferation.

Low light energy inserted into cells proliferates and stimulates collagen production and induces collagen and elastic tissue synthesis.

Lubart and colleagues (1993) investigated the effect of light intensities on mammalian cells, they found that the induction of fibroblast proliferation at a constant dose depends on the applied intensity in a non linear manner. Moreover, they demonstrated distinct combinations of dose and intensity at which the induction of cell proliferation was maximal in a wavelength dependent manner. Van Breughel (1992) irradiated fibroblast cultures at a constant dose varying intensities and exposure time. Results show that the proliferation and collagen production could be only stimulated with medium intensities and exposure times.

The Crystal 512 and Record 618 uses specific dose, intensity and wavelengths that enable it to stimulate the cells to produce more collagen and thus rejuvenating the skin.

Acne treatments

There are five different kinds of Acne:

1. Acne vulgaris: it is a clogging of the hair follicles that leads to unsightly, and sometime painful, skin lesions and pimples.

2. Acne conglobata: It usually affects males, it covers the back, chest, and buttocks with pustules and nodules, which often connect under the skin, which might cause a severe bacterial infection, as well as extensive scarring.

3. Acne cosmestica: It is triggered by topical make up. Characterized by small pink bumps.

4. Acne medicamentosa: Caused by sensitivity to drugs and medicines.

5. Acne rosasecea: It is rather an inflammation of the face, neck or chest.

Photo therapy, is most effective in types 1, 2 & 5, in those types a bacterial action is present especially P. acnes which tend to produce endrogenous porphyrins (mostly coproporphyrin III) as a part of its normal metabolism. High intensity broad spectrum light is absorbed in the photo excitation process and releases a sing-let oxygen, who proves to be fatal to the bacteria, and effectively clear inflammation in a fraction of time it takes for standard topical or oral treatments to do the same. This reaction is confined to the bacteria and has no effect on surrounding tissue.

The Acne starts when the opening of the hair follicle is blocked. The bacteria that leave inside the hair follicle (P. Acne) starts to multiply rapidly and the bodies immune system tries to fight the bacteria – starting an inflammation. And the Acne appears. As long as the bacterial activity continues the inflammation continues and the Acne flourish.

The intensive light releases an oxygenator that eliminates the bacteria, thus ending the inflammation and the Acne.

www.active2001.com

Collagen fillers

Collagen fillersThese collagen fillers are extracted from cow hide which is processed, purified and sterilized into a liquid form. A thin gauge needle is then used to inject the collagen into the skin.

Great care must be taken by the plastic surgeon when placing the collagen injection fillers, as placement too deep in the skin will not help the wrinkle, while a too superficial placement in the skin could result in the area persistently feeling like “beading”.

• Revanesse Ultra is high viscosity, biodegradable, non-animal based clear Hyaluronic acid gel. It is a longer lasting filler that is used for smoothing out the deeper wrinkles and folds, such as glabellar folds, peri-oral wrinkles, nasolabial folds, oral commisure creases around the mouth, chin/cheek augmentation, and is great for adding volume to the lips. Revanesse will last longer in the skin, but will down naturally at the implant site after about 6-12 months without leaving any harmful by-products

•Revanesse Ultra and ReDexis
ReDexis is a natural dermal filler that regenerates the skin and is designed to treat deeper lines, wrinkle folds, and lip augmentation. Redexis can last from 12 to 18 months and acts not only as a filler but as a regenerator. The result is a natural looking and feeling dermal filler,that replaces lost collagen, and regenerates the dermis.
Over time, skin loses its natural abundance of hyaluronic acid, which is a natural occurring acid found in the skin and is the component of extra cellular matrix. As the Revanesse family is the newest hyaluronic acid based filler it provides the doctors, and patients, with a dermal filler that is easy to inject, rejuvenates the skin and contains the highest concentration of Hyaluronic Acid Available.

•RESTYLANE AND PERLAINE
One of the great advantages of Perlane is that it is long-lasting, but not permanent. Unlike permanent treatments or implants, Perlane always leaves you with the option of re-evaluating your needs when the initial effect has worn off. With Perlane, you will always have the option of continuing or changing the combination of treatments. A follow-up can be performed at any time you like after the previous treatment.

Perlane is made in Sweden, a nation known for health, nature, beauty and high-quality products. After decades of extensive research, Dr. Bengt Ågerup and the company Q-Med in Uppsala, Sweden, succeeded in developing a method to manufacture non-animal, stabilized, hyaluronic acid in the form of a gel, called NASHA. The first application, Perlane, was launched in 1996.

Impressions of beauty change with time – as do our faces as we age. With Perlane, you can have a natural beauty lift with the body’s own material. Perlane is a crystal-clear, non-animal, biodegradable gel based on a natural substance, called hyaluronic acid. The gel is injected into the skin in tiny amounts with a very fine needle. The result is instantaneous and for many people a fuller and more sensuous mouth comes high on their wish list. With Perlane, you can enjoy a more pronounced mouth or a soft pouting look with the body’s own material.

 The natural healing centre

Mesotherapy

MesotherapyMesotherapy for the Face?
Multiple factors contribute to accelerated aging and wrinkles in the face. Primarily over exposure to sunlight (photo aging), free radicals, poor nutrition, hormonal imbalances, and extreme stress (malfunctioning within the brain-beauty connection) are among the most common. All will lead to skin irregularities, dehydration, and a progressive loss of collagen and elastin (essential for maintaining youthful tone and moisture and suppleness).

Mesotherapy skin rejuvenation utilizes the dermal infusion technique (multiple tiny injections) to deliver pharmaceutical, natural medications, vital antioxidants, vitamins, minerals, and amino acids, fat dissolvers and other substances to nourish the deficient intracellular levels. The tiny injections work to stimulate a multitude of cellular receptor sites, which signal the brain-body-beauty axis to produce collagen and elastin, reduce wrinkling, while replenishing cellular hydration.

After a series of treatments, patients will notice a positive change in skin tone, suppleness, and elasticity. The treatment promotes significant tightening and lifting effects within the skin, revealing an overall rested youthful appearance.

Mesotherapy skin rejuvenation is extremely effective and can be safely used in combination with other anti-aging procedures and treatments. Signature treatments include Botox®, Collagen fillers, Face Fat Removal, Restylane, Revanesse, ReDexis, Perlane, Juviderm, Jet PeelTM Peeling.

The natural Healing centre

MESOTHERAPY

MESOTHERAPY

This well-known and accepted therapeutic process, invented in 1952 by Dr. Michael Pistor (France), is an alternative medicinal therapy that requires quire rigorous procedures and is applied in the safest conditions. It can only be practiced by a qualified and experienced medically trained professional, with additional training in Mesotherapy.
This therapeutic process is now practiced in many countries of the world. Zina Chervinska has been successfully practicing Mesotherapy in Canada since 2003.

Mesotherapy is a treatment that stimulates the mesoderm, or middle layer of the skin. It is done with homeopathic agents containing placenta, nucleoproteins, oligo-elements and vitamins.

Medication

Medication is administered subcutaneously with special disposable micro needles. Micro-drops of the drug are slowly absorbed into the blood flow; the results usually become visible after the first treatment. Other treatments include a lifting mask and colour therapy which help to smooth out wrinkles and reduce a double chin. Flaccid skin, acne scars and fatty deposits also respond to this treatment

What Mesotherapy can do
it can help in the treatments of:

  • Face, Neck rejuvenation
  • Alopecia
  • Wrinkles
  • Hyperkeratosis
  • Cellulite, Reduction
  • Hyper pigmentation
  • Weight loss, Fat loss
  • Arthritis pain
  • Flaccid skin
  • Migraine headaches
  • Acne, Scars
  • Tendonitis
  • Seams and scars
  • Sport trauma
  • After-delivery distention
  • Stretch marks
  • Thinning hair
  • Bone spurs

Mesotherapy, which is sometimes called rehabilitation therapy, can make individuals look younger as well as stimulating your body and its immune system.
Side effects and restrictions

Side effects of the procedure may be a possible reddening, swelling and/or bruising around the area of the injections. These symptoms generally disappear in a matter of hours. Mesotherapy is generally suitable for most people, including children and those with diabetes. There are no age restrictions.

General restrictions vary with conditions treated and will be discussed before treatments are administered. You can not wear makeup for four hours after Mesotherapy. You can not vigorously exercise for 48 hours. No hot showers are allowed for 6 to 8 hours after treatments. It is also recommended to eat a meal high in protein prior to treatment.

The Canadian Mesotherapy Association

IMEDEEN’s Skin Rejuvenating Tablets III

IMEDEEN’s Skin Rejuvenating Tablets
How It Works
Can IMEDEEN be taken over a longer period of time?
Can I take IMEDEEN permanently?
As IMEDEEN’s skin rejuvenating tablets are a food supplement with natural ingredients, there is no indication that one should not take it as long as desired. IMEDEEN’s skin rejuvenating tablets are developed to be a permanent part of your daily skincare routine. Clinical studies have shown that IMEDEEN tablets are safe for long-term use. An efficacy and safety study carried out over 12 months clearly demonstrates this. IMEDEEN’s skin rejuvenating tablets have also been through rigorous toxicological tests, confirming that they are a safe product. Furthermore, we know of loyal consumer and celebrities who have used IMEDEEN Classic, IMEDEEN’s first skin rejuvenating tablets, ever since its launch, back in 1991.

What happens if I stop taking IMEDEEN?
The condition your skin was in before you started taking IMEDEEN’s skin rejuvenating tablets was the result of many years of skin deterioration. Similarly, should you stop using IMEDEEN’s skin rejuvenating tablets, the results you have obtained will not disappear overnight, but will recede gradually. While we have not examined the pace at which this happens, we know from consumer experiences that it varies from person to person; some say after as little as one month and others have reported from four to six months.
Does IMEDEEN show an effect on other parts of the body?
Yes. During the studies, the effects of IMEDEEN’s skin rejuvenating tablets in the face have been shown by ultrasound measurements and clinical grading. Furthermore, in the Imedeen Prime Renewal study, the skin on the hands and on the décolletage (upper part of the chest) were investigated with equally good results. In the IMEDEEN Time Perfection study, 67% of the women taking the product noticed improved texture and decreased dryness on the skin all over their bodies.
Can IMEDEEN help oily skin?
We have not evaluated the beneficial effects of IMEDEEN’s skin rejuvenating tablets on oily skin, so we do not have any documented benefits for this skin type.
Does IMEDEEN protect the skin against sunburns?
IMEDEEN’s skin rejuvenating tablets does not work as a sun protector – always use a sunscreen with an appropriate SPF when outside.
Does IMEDEEN have effect on hair and nails?
We have not performed clinical studies covering hair and nails.
My day cream contains antioxidants (Vitamins C and E).
Do IMEDEEN and creams work together or against each other?
IMEDEEN’s skin rejuvenating tablets and creams, lotions, etc., work in different ways and affect different layers of the skin. Being tablets, they work from within the body. The ingredients are transported to the dermis (the supportive layer of the skin) via the blood, where they effectively assist in defending the skin structure against the harmful effects of free radicals. Creams and lotions work in the epidermis, so IMEDEEN’s skin rejuvenating tablets and creams or lotions containing antioxidants complement each other.
Formula and Ingredients
What is Biomarine Complex?
The Biomarine Complex, exclusive to IMEDEEN’s skin rejuvenating tablets, is a fish extract rich in proteins and polysaccharides. These proteins are similar to the proteins found in the dermal layer of the skin – collagen, elastin and fibrillin. It has conclusively shown to improve skin density. Polysaccharides are the sugar molecules that create the moisture binding gel-like substance in the skin. These molecules can bind up to 1,000 times their weight in moisture and are responsible for the skin’s hydration. Biomarine Complex has in several scientific studies shown to improve skin’s density and moisture content.
What is the difference between fish protein in IMEDEEN and the fish oils talked about in the news?
Fish oils are an energy source and building blocks for cell membranes while fish proteins are building blocks for various proteins including collagen, fibrillin, and elastin, which are important to the structure and density of the skin.

Fish proteins contain high amounts of both essential and non-essential amino acids. Amino acids are direct building blocks for numerous vital proteins in the body. The skin is no exception. Of special importance in the skin is collagen, fibrillin, elastin and other supportive protein, important for the structure and density of the skin. Fish proteins contain high amounts of amino acids and peptides directly involved in the formation (synthesis) of collagen, fibrillin and elastin.

Fish oils are made of fatty acids and glycerol. Their main function in the body, including the skin, is as an energy source and building blocks for cell membranes. Fish oils contain a large proportion of omega-3 fatty acids which play an important role in maintaining membrane fluidity (= flexibility).
What is an antioxidant?
An antioxidant helps defend the skin against the signs of aging by neutralizing free radicals. Found naturally in the body and skin, antioxidants are stable molecules from which free radicals can “steal” an extra electron. Once they have acquired an extra electron, free radicals are neutralized. In this way, antioxidants effectively help defend the skin against free radicals, thus aging.
What is lycopene?
Lycopene is the pigment that gives ripe tomatoes and watermelons their bright red color. Its molecular configuration makes it one of the best natural free radical scavengers. It plays an important role in defending lipophilic (fat-based) environments, such as the cell membranes, against degradation by free radicals.
Where does the lycopene in IMEDEEN come from?
The lycopene is extracted from red, ripe, specially grown, non-genetically modified tomatoes.
What is grape seed extract?
Grape seed extract effectively decreases the amount of free radicals in aqueous (water-based) environments such as cell plasma. Furthermore, it accumulates in connective tissue that is rich in proteins and polysaccharides, such as the skin.
Are there any additives in IMEDEEN?
IMEDEEN’s skin rejuvenating tablets are based on natural ingredients. They do not contain lactose, added sugar, preservatives or artificial flavoring.
Does IMEDEEN contain fat? Will the use of Imedeen cause weight increase?
IMEDEEN’s skin rejuvenating tablets do not contain fat. Furthermore, six month’s intake of IMEDEEN’s skin rejuvenating tablets showed no change in weight on average..
Is IMEDEEN kosher?
The Biomarine Complex in IMEDEEN’s skin rejuvenating tablets is not kosher.
Who Can Benefit?
Who can benefit from IMEDEEN?
IMEDEEN’s skin rejuvenating tablets are recommended to everyone who wishes to maintain a beautiful, healthy and natural appearance. These tablets are recommended for women with dry to normal skin from the age of 35 up – possibly earlier if the skin shown signs of photo-aging. IMEDEEN’s skin rejuvenating tablets come in two types that are specifically formulated for different life phases – IMEDEEN Time Perfection for women aged 35 to 50, and IMEDEEN Prime Renewal for women who are post menopause, which is generally age 50+.
When and How to Use it
How should IMEDEEN be stored?
IMEDEEN’s skin rejuvenating tablets are optimally protected in the aluminum foil packaging. For best results, leave the tablets in the original packaging until use. Store IMEDEEN’s skin rejuvenating tablets in a dry, cool (below 86°F) place, away from children.
What should I do if I forget to take one, two or more tablets?
Don’t worry – we recommend that you just continue taking the recommended dose of tablets per day.
Can I take IMEDEEN while I am pregnant or breast feeding?
IMEDEEN’s skin rejuvenating tablets are a natural-based supplement. We recommend, however, that pregnant and breast-feeding women, in general, do not take any food supplements unless recommended by their doctor.
Safety
What about safety? Does IMEDEEN have any side effects?
IMEDEEN’s skin rejuvenating tablets contains fish and soy proteins and may, like other food products, cause allergic reactions. If you have experienced allergic reactions to these ingredients in the past, do not take IMEDEEN’s skin rejuvenating tablets. Some people experience slight skin reactions, such as appearance of small pimples. These will normally disappear within four weeks of continued use. If they do not disappear, we recommend that you stop using IMEDEEN’s skin rejuvenating tablets.
Can I take IMEDEEN together with other antioxidants?
Yes, IMEDEEN’s skin rejuvenating tablets are based on natural ingredients in doses that can be taken in combination with other vitamin and mineral supplements. It is safe to include as a regular part of your diet along with vitamins, health foods and other dietary supplements.
Does IMEDEEN carry any precautions?
IMEDEEN’s skin rejuvenating tablets contain fish proteins and traces of soy proteins and may, like other food products, cause allergic reactions. Therefore, there is a precaution on the package stating that people with known allergies to fish and soy proteins should not take IMEDEEN’s skin rejuvenating tablets. People suffering from a serious illness or people under medical supervision should not take any food supplements in general without checking with their doctor or health professional.
Can IMEDEEN be taken in combination with other dietary supplements?
IMEDEEN’s skin rejuvenating tablets contain natural-based ingredients in doses that can be taken with other vitamin and mineral supplements. It is safe to include IMEDEEN’s skin rejuvenating tablets as a part of your regular diet along with vitamins, health foods and other dietary supplements. However, you should always be aware of the total intake of supplements.
Can I take IMEDEEN with medication?
It is unlikely that IMEDEEN’s skin rejuvenating tablets will adversely interact with pharmaceuticals. However, we recommend that people suffering from a serious illness and who are under medical supervision in general do not take food supplements without consulting their doctor.
Can I take IMEDEEN and Hormone Replacement Therapy (HRT)?
In the clinical study on IMEDEEN Prime Renewal, no adverse events were reported for the women taking HRT together with the product. As IMEDEEN Prime Renewal is a dietary supplement, an interaction with HRT is unlikely to occur.
Can people who have thyroid problems take IMEDEEN?
Ferrosan A/S recommends that people suffering from a serious illness and who are under medical supervision should in general not take any food supplements unless recommended by the doctor.
Can diabetics take IMEDEEN?
IMEDEEN’s skin rejuvenating tablets do not contain added sugar. However, Ferrosan recommends that people suffering from a serious illness or people who are under medical supervision do not take any food supplements unless recommended by the doctor.

Nordic Selfcare Institute